Apixaban is available in the form of a tablet, which is usually taken twice a day, every twelve hours. Patients should consult with their doctor to discuss their recommended daily Apixaban dosing. After taking the oral dose, the maximum concentration of the medicine is reached in three to four hours, and its concentration decreases by 50% within twelve hours.
The dose of Eliquis (Apixaban) may vary depending on the individual patient and the medical condition for which it is being prescribed. The dosage will generally be determined by the number of doses taken per day, the time between doses, and the length of time the medication is taken. You should follow your doctor’s instructions or the directions on the label when taking this medication. The average doses of this medicine are listed below, however, you should not make any changes to your dose without first consulting with your doctor.
For Prevention of Deep Venous Thrombosis (Hip Replacement Surgery):
- Adults: 2.5 milligrams (mg) two times a day, for 35 days. The first dose should be taken 12 to 24 hours after surgery.
- Children: Use and dose must be determined by your doctor.
For Prevention Deep Venous Thrombosis (Knee Replacement Surgery):
- Adults: 2.5 milligrams (mg) two times a day, for 12 days. The first dose should be taken 12 to 24 hours after surgery.
- Children: Use and dose must be determined by your doctor.
For Prevention of Reoccurring Deep Venous Thrombosis and Pulmonary Embolism:
- Adults: 2.5 milligrams (mg) two times a day, after at least 6 months of treatment for deep venous thrombosis or pulmonary embolism.
- Children: Use and dose must be determined by your doctor.
For Prevention of Strokes and Blood Clots in Patients with Non-Valvular Atrial Fibrillation:
- Adults: 5 milligrams (mg) two times a day.
- Adults with 2 of the following characteristics: 80 years of age and older, body weight of 60 kilograms (kg) or less, or kidney problems—2.5 mg two times a day.
- Children: Use and dose must be determined by your doctor.
For Treatment of Deep Venous Thrombosis and Pulmonary Embolism:
- Adults: At first, 10 milligrams (mg) two times a day, for the first 7 days. Then, your doctor may give you 5 mg two times a day.
- Children: Use and dose must be determined by your doctor.
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